An occlusion device comprises a distal end, a proximal end and an elastic braided body which is provided between the proximal end and the distal end and made of wires. The elastic boy is composed of a multi-stage braided net, which comprises at least a first-stage braided net that is closest to the distal end and made of a plurality of first-stage wires, and a second-stage braided net which is braided by a plurality of first-stage wires and second-stage wires all together. The minimum cross-section area of the first-stage braided net after being compressed toward the direction perpendicular to an axis of the elastic braided body is less than the minimum cross-section area of any other-stage braided net after being compressed toward the axis. A method of manufacturing the occlusion device is also provided.