Christopher E. Szymczak,Frank J. Bunick,Harry S. Sowden,Joseph R. Luber,Leo B. Kriksunov
申请号:
US13052219
公开号:
US08858210B2
申请日:
2011.03.21
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention features the present invention features a tablet including at least one pharmaceutically active ingredient, wherein the shape of said tablet includes at least one major face wherein: (i) the peak penetration resistance at the perimeter of said major face of the tablet is at least about 10% greater than the peak penetration resistance at the center of said major face and (ii) the tablet disintegrates in the mouth when placed on the tongue in less than about 30 seconds, and a machine and method for manufacture of such tablet.