Brad J. SPELLBERG,Ashraf S. IBRAHIM,John E Edwards, JR.
申请号:
US13418263
公开号:
US20120171175A1
申请日:
2012.03.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention is based, in part, on the discovery of a novel cell-based immunotherapy that can recapitulate neutrophil functions in neutropenic individuals afflicted with a microbial infection. The therapeutic methods of the invention are broadly applicable to treat any infection in a neutropenic individual, including infections caused by bacteria, fungi, protozoa, and viruses. The methods of the invention represent a practical, rapid cell-based immunotherapy for refractory infections comprising compositions of activated, irradiated HL-60 cells.