Aqueous solution, cream, hydrogel or spray composition containing compound Sn-On-Xn； where S(n=5-8), O (n=3-7) and X═Fe, Cr or Ni, and most effectively, S7-O4-Fe4 as active ingredient for cutaneous, intradermal and subcutaneous treatment of dermo-epithelial lesions, comprising but not limited to, certain types of skin cancer (basal cell, keratocanthoma and spinocellular carcinomas), conjunctivitis, folliculitis, acne, gingivitis, stomatitis, fungal, dermatomycosis, parasitosis, condylomatosis, balanitis, vaginitis, vaginosis, bacteriosis and endometriosis； by reducing the number of infecting microorganism, not limited to Candida sp., Actinobacillus actinomycetemcomitans, Pseudomonas sp., Porphyromonas gingivalis., Escherichia, sp., Staphyloccocus sp. Streptococcus sp., Herpes simplex I, Herpes simplex II, Coxackievirus A and B, Echovirus, Varicella Zoster (HHV-3), Human Papilloma Virus Gardnerella Vaginalis, Trichomonas vaginalis, Corynebacterium sp., present on the body skin and mucosas. Treating condition may include other abnormal conditions of the skin and epithelium, including insect bites, leukoplakia, oral (aphthous) ulcers and burns, trauma, aphthous, herpervirus infections, stomatitis, herpangina (mouth blisters), a painful mouth infection caused by coxsackieviruses.
