A method of laser ocular surgery for treating glaucoma is disclosed. The method can include imaging a treatment eye to obtain an image of the treatment eye and aligning a laser on a region of the treatment eye based on the image of the treatment eye. The method can also include firing a plurality of laser pulses from the laser to ablate tissue in the region of the treatment site, wherein the tissue ablation creates micro-perforations in the region of the treatment site to incite an inflammatory reaction.