A method of acquiring an image biomarker suitable for prognosis of a blood-related disease, such as acute myeloid leukemia, includes the steps of: (a) acquiring physical parameter sets, each including at least two parameters, respectively from time-signal intensity curves, these curves being respectively obtained from magnetic resonance image sets of different subjects each of the image sets being acquired through MRI scanning using one of first and second configuration parameter sets (b) analyzing the physical parameter sets thus acquired and (c) establishing a risk score function that is a sum of products of each of the physical parameters and the corresponding weight value, wherein a risk score obtained using the risk score function serves as the image biomarker suitable for prognosis of the blood-related disease.
