PROBLEM TO BE SOLVED: To provide a compound that has an amyloid β protein production inhibitory action and especially a β cretase (BACE1) antagonism, and that is useful for a medical treatment or a preventive to a disease induced by production, excretion and/or deposit of the amyloid β protein.SOLUTION: A compound that is represented by the formula (I) or a pharmaceutically acceptable salt thereof is disclosed. In the formula, R1 and R2 are an alkyl group or the like R3 and R4 are a hydrogen atom, a halogen atom or the like a ring A is a benzene ring or a 5-member heteroaromatic ring and a ring B is a pyridine ring or the like.COPYRIGHT: (C)2014,JPO&INPIT【課題】アミロイドβ蛋白質産生抑制作用、特にβクレターゼ(BACE1)阻害作用を有し、アミロイドβタンパク質の産生、分泌及び/又は沈着により誘発される疾患の治療又は予防剤として有用な化合物の提供。【解決手段】式(I)で表される化合物又はその製薬上許容される塩。[R1及びR2はアルキル基等であり、R3及びR4は水素原子又はハロゲン原子等であり、環Aはベンゼン環又は5員芳香族複素環あり、環Bはピリジン環等である。]【選択図】なし
