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APPAREIL DE TRAITEMENT DE CELLULES PATHOLOGIQUES
专利权人:
TOFANI; Santi
发明人:
XI, Chen,SHIQIANG, Shang,HUAMEI, Li,ZHENG, Shen,CAN, Wang,LINQING, Yuan,KEXIN, Shi,CHAO, Yang,SUCHEN, Bian,JINHU, Wang,KUN, Zhu,MIN, Yang,WEIZHONG, Gu
申请号:
IBIB2018/050765
公开号:
WO2018/172863A1
申请日:
2018.02.07
申请国别(地区):
IB
年份:
2018
代理人:
摘要:
An electromagnetic field generating apparatus for treating pathological cells, in particular with tumor suppression function. The ratio of static magnetic field to alternating magnetic field is in the range of 0.5-2.5, and the total intensity is in the range up to 100 imT. It provides non-invasive low toxicity and side effects, significantly inhibiting a plurality of tumors, influencing the intracellular superoxide radical content, and promoting cell autophagy. The mechanism of action of the magnetic field is on the electron spin energy levels and consequently on the free radicals concentration. Additional magnetic field having frequency up to 100 MHz and intensity down to microTesla range can be also used to improve the antitumor efficacy in combination with the static as well as the extremely low frequency electromagnetic field (1 -300 Hz) influencing the spin hyperfine resonance. A combination method is also provided of a power- frequency electromagnetic field generating device and a platinum-based medicine. The in vitro and in vivo experiments confirmed that the tumor therapeutic electromagnetic field combined with platinum-based chemotherapy drugs can enhance the efficacy of platinum-based chemotherapy drugs and magnetic field alone, a significant inhibition of a variety of tumors; can reduce the dose of cisplatin and reduce side effects.L'invention concerne un appareil de génération de champ électromagnétique pour traiter des cellules pathologiques, en particulier avec une fonction de suppression de tumeur. Le rapport du champ magnétique statique au champ magnétique alternatif se situe dans la plage de 0,5 à 2,5, et l'intensité totale est dans la plage allant jusqu'à 100 imT. L'invention permet d'obtenir de faible toxicité non invasive et effets secondaires, d'inhiber de manière significative une pluralité de tumeurs, d'influencer le contenu de radicaux superoxydes intracellulaires et de favoriser l'autophagie cellulaire. Le mécanisme d'action du champ magnéti
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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