INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC.; LTD.;OTSUKA PHARMACEUTICAL CO.;OTSUKA PHARMACEUTICAL CO., LTD.
发明人:
KUBO, HIROSHI,SOGO, SHINJI,SUGIYAMA, HARUO
申请号:
EP13864968
公开号:
EP2933261A4
申请日:
2013.12.16
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention relates to a method for activating helper T cells, which includes the step of activating helper T cells by adding a WT1 peptide to antigen presenting cells, wherein the WT1 peptide has the ability to bind to an MHC class II molecule selected from HLA-DRB1*08:02 molecule, an HLA-DRB1*13:02 molecule, an HLA-DRB1*14:03 molecule, an HLA-DRB1*14:05 molecule, an HLA-DQB1*03:02 molecule, and an HLA-DQB1*04:01 molecule.