A medicament delivery device includes a housing a drive force mechanism slidable in the housings distal part a member connected to the drive force mechanism for holding it in a loaded state and axially movable in relation to the distal part a predetermined distance by the housings proximal part when the parts are moved toward each other and an actuation member to be biased in relation to the distal part from a non-operating position partially protruding from the distal part to an operating position confined within the distal part. The actuation member can release the drive force mechanism from its loaded state, and is resiliently connected to the distal part such that it is always recoiled after being biased regardless of whether the actuation mechanism is released. The drive force mechanism is released only after the holding member moves and the actuation member is biased from non-operating to operating position.