Weiser, Michael,Capriotti, Joseph,Stein, Jason,Liang, Bo,Samson, C.
申请号：
NZ75191510
公开号：
NZ751915A
申请日:
2010.12.15
申请国别(地区):
NZ
年份:
2020
代理人:
摘要：
A ophthalmic preparation comprising: a. povidone-iodine at a concentration from about 0.1 % to about 2.5% said ophthalmic preparation, b. at least one member selected from the group consisting of a lubricant and a cooling agent, at a concentration which is not irritating to the eye； and c. optionally, one or more of the members selected from the group consisting of camphor, borneol, a lubricant, an emollient, a steroidal anti-inflammatory compound, and a non-steroidal anti-inflammatory compound. The compositions are useful to relieve mild ocular irritation, enhance ocular comfort, and to provide a refreshing effect and improved sensation, when the povidone-iodine solution is applied to the eye. An exemplary composition would be: 0.36%, 0.48%, or 0.6% PVP-I, by weight, as desired in the final product, and combining with 0.5% carboxymethylcellulose sodium, boric acid, calcium chloride, magnesium chloride, sodium borate, sodium chloride, and purified water. In an embodiment, a preserved ophthalmic solution comprises hydrochloric acid and/or sodium hydroxide to adjust pH.
