Daniel James Ford,Qiuya Huang,Judi Charlotte Neuss,James Thomas Reuberson,Bart Vanderhoydonck
申请号:
US15924020
公开号:
US20180201622A1
申请日:
2018.03.16
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A series of fused bicyclic heteroaromatic derivatives of formula (IA) or (IB), as defined herein, being selective inhibitors of phosphatidylinositol-4-kinase IIIβ (PI4KIIIβ) activity, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases and malaria; and organ and cell transplant rejection.