#$%^&*AU2012227308A120121018.pdf#####- 23 PATENT 00961-PO4358WO SPM/AJD ABSTRACT A cosmetic method of improving the appearance of aging skin, including peri-menopausal, menopausal, or post-menopausal skin, comprising applying to the skin tissue an effective amount of a composition comprising S-palmitoyl glutathione and a dermatologically acceptable carrier.