Systems and methods are provided for monitoring medication compliance to allow a doctor or medical care provider to determine whether a subject is ingesting a prescribed medication. A medication container includes a plurality of medication containing cells with frangible covers overlaying each cell. An electrical circuit includes a sequential value element associated with each cell with the sequential value elements being connected in parallel and having a unique value. When the cover of a cell is broken the associated sequential value element is uncoupled from the electrical circuit. A measurement device calculates the combined value of the sequential value elements coupled to the electrical circuit to determine which of the cells have been accessed via breakage of the associated cover.
