METHOD FOR GENERATING T CELLS PROGENITORS

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专利权人:

Institut National de la Santé et de la Recherche Médicale;Université Paris Descartes;Assistance Publique - Hopitaux de Paris;Fondation Imagine - Institut des Maladies Génétiques

发明人:

Isabelle André,Marina Cavazzana,Kuiying Ma,John Tchen

申请号：

US16485488

公开号：

US20200046767A1

申请日:

2018.02.12

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The invention relates to an in vitro method to generate T cell progenitors, comprising the step of culturing CD34+ cells in a medium containing TNF-alpha and/or an antagonist of the Aryl hydro-carbon/Dioxin receptor, in particular StemRegenin 1 (SR1), in presence of a Notch ligand and optionally a fibronectin fragment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/