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INHIBITION OF PRMT5 TO TREAT MTAP-DEFICIENCY-RELATED DISEASES
专利权人:
NOVARTIS AG
发明人:
Konstantinos John MAVRAKIS,Earl Robert MCDONALD, III,Frank Peter STEGMEIER
申请号:
US15510542
公开号:
US20180010132A1
申请日:
2015.09.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides novel personalized therapies, kits, transmittable forms of information and methods for use in treating patients having cancer, wherein the cancer is MTAP-deficient and/or MTA-accumulating and thus amenable to therapeutic treatment with a PRMT5 inhibitor. Kits, methods of screening for candidate PRMT5 inhibitors, and associated methods of treatment are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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