Konstantinos John MAVRAKIS,Earl Robert MCDONALD, III,Frank Peter STEGMEIER
申请号:
US15510542
公开号:
US20180010132A1
申请日:
2015.09.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides novel personalized therapies, kits, transmittable forms of information and methods for use in treating patients having cancer, wherein the cancer is MTAP-deficient and/or MTA-accumulating and thus amenable to therapeutic treatment with a PRMT5 inhibitor. Kits, methods of screening for candidate PRMT5 inhibitors, and associated methods of treatment are also provided.