A needle and hub assembly for automatic injectors includes a cap or skirt that has a forward surface interposed between and reinforced by first and second engaged hub portions. A needle is received in a contiguous channel formed in the two hub portions. Methods of forming the assembly include molding the first hub portion, placing the cap over the first hub portion, inserting the needle into the channel in the first hub portion, and then overmolding or otherwise forming the second hub portion on the exterior of the first hub portion and cap such that the second hub portion engages the first hub portion. An assembly created by this &ldquo；two-shot&rdquo； process can be used to seal a relatively large opening in a medicament cartridge and to support the needle more effectively than a conventional assembly.
