An anatomically designed egg-shaped or elliptical-shaped nasopharyngeal airway for providing a comfortable and safe air passage through a nose to a nasopharynx includes a cannula having a proximal open end, a distal end, and a sidewall surrounding a lumen of the cannula. The nasopharyngeal airway has a port, which includes two or more openings separated by one or more bridges, in the sidewall, at a distal portion of the cannula. Upper and lower conduits may be located in channels of the sidewall of the cannula for delivery of oxygen and measurement of CO2 or other purposes.