The invention relates to a sulfur-containing compounds of formula 1, wherein R 2 is S or SO 2 and R 1 , R 3 and R 4 are as defined in the claims, and the preparation thereof. The invention also relates to the uses of the sulfur-containing compounds in inhibiting inducible nitric oxide synthase and/or cyclooxygenase-2 and in treating the diseases associated with inducible nitric oxide synthase and/or cyclooxygenase-2.本發明係關於一種含硫化合物及其製造方法。本發明另關於該含硫化合物於抑制誘發型一氧化氮合成酶(inducible nitric oxide synthase，iNOS)及/或第二型環氧合酶(cyclooxygenase－2，COX－2)之作用與用以治療與其相關疾病之應用。
