KYOTO UNIVERSITY;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
Noboru ASHIDA,Masayuki YOKODE,Michael KARIN,Dat NGUYEN TIEN
申请号：
US14439885
公开号：
US20150320020A1
申请日:
2013.10.31
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides a non-human animal IKKβ which shows fibrosis of tissue, since it lacks IKKβ gene in a myofibroblast- and/or smooth muscle cell-specific manner. Since the non-human animal shows pathology highly similar to scleroderma, it is extremely useful as an animal model of scleroderma.
