Novel benzimidazole derivatives as kinase inhibitors

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专利权人:

Selvita S.A.

发明人:

Czardybon, Wojciech,Brzozka, Krzysztof,Galezowski, Michal,Windak, Renata,Milik, Mariusz,Zawadzka, Magdalena,Guzik, Pawel,Wincza, Ewelina,Prokop, Marta,Wiklik, Katarzyna,Sabiniarz, Aleksandra,Cholody,

申请号：

AU2013366513

公开号：

AU2013366513B2

申请日:

2013.12.20

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The present invention relates to derivatives of benzimidazoles of formula (I) as disclosed herein as well as pharmaceutical compositions comprising said derivatives. The derivates according to the present invention are serine/threonine and tyrosine kinase-inhibitors, particularly of PIM1-3-and DYRK1A-kinases and may particularly be used in the treatment of diseases linked to these kinases, such as e.g. leukemias, lymphomas, solid tumors and autoimmune disorders.

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