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Fluorescent membrane intercalating probes and methods for their use
专利权人:
发明人:
Brian D. Gray
申请号:
US14522156
公开号:
US09597416B2
申请日:
2014.10.23
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to a family of dyes which fluoresce in the UV-VIS, far red and near infrared wavelengths of the spectrum and possess asymmetric lipophilic alkyl chains. The dyes of the invention are soluble in commercially available membrane staining vehicles, are useful as probes for rapidly staining lipophilic structures such as membranes in cells or isolated from cells, and are well-retained therein. Methods of utilizing the dyes to detect stained cells both in vivo and in vitro are also disclosed.
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