The system has a coupling part (11) to couple a lancet to a drive (21) to generate a pricking movement and a sampling device (9) to the drive to generate a sampling movement. The part moves from a starting position respectively during the pricking and sampling movements into an end position, with an advancing motion, and from the end position into the starting position with a reversing motion. A movement control system causes the part to reach an end position laterally staggered in relation to the end position reached by the coupling part during the pricking and sampling movements.