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Use of specific regulatory T-cells to induce immune tolerance
专利权人:
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
发明人:
Scott David W.,Kim Yong Chan
申请号:
US201414889962
公开号:
US10093901(B2)
申请日:
2014.05.09
申请国别(地区):
美国
年份:
2018
代理人:
Foley & Lardner LLP
摘要:
The present invention generally relates to the production of antigen-specific T regulatory cells (Tregs). Such cells can be used in therapy to minimize undesirable immune responses such as those observed in autoimmunity and hemophilia and other diseases as well as in the response to protein therapy for genetic diseases. Methods for producing antigen specific Tregs and conditions for preferential expansion of functionally stable, specific Tregs are also provided.
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