William Gregory Hundley;Craig A. Hamilton;Frank Torti;Kimberly Lane;Tim Morgan
发明人:
William Gregory Hundley,Craig A. Hamilton,Kimberly Lane,Tim Morgan,Frank Torti
申请号：
US12019457
公开号：
US08532739B2
申请日:
2008.01.24
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Evaluating tissue characteristics including identification of injured tissue or alteration of the ratios of native tissue components such as shifting the amounts of normal myocytes and fibrotic tissue in the heart, identifying increases in the amount of extracellular components or fluid (like edema or extracellular matrix proteins), or detecting infiltration of tumor cells or mediators of inflammation into the tissue of interest in a patient, such as a human being, is provided by obtaining a first image of tissue including a region of interest from a first acquisition, and obtaining a second image of the tissue including the region of interest during a second, subsequent acquisition. The subsequent acquisition may be obtained after a period of time to determine if injury has occurred during that period of time. Such a comparison may include comparison of mean, average characteristics, histogram shape, such as skew and kurtosis, or distribution of intensities within the histogram.
