Pharmaceutical composition for treating intervertebral disc degeneration, low back pain improvement, and therapeutic drug screening method

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专利权人:

学校法人慶應義塾

发明人:

松本 守雄,中村 雅也,藤田 順之,鈴木 悟士,中島 大輔

申请号：

JP2017528983

公开号：

JP6251849B2

申请日:

2016.10.13

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

N-acetylcysteine (NAC) or tocopherol has been found effective as a therapeutic drug for improving intervertebral disc degeneration as well as low back pain and other diseases caused thereby. Oxidative stress has been revealed as one of the factors responsible for intervertebral disc degeneration. Hence, the present invention provides a method for screening for an intervertebral disc degeneration and/or low back pain drug targeting oxidative stress. Furthermore, an approach capable of quantitatively evaluating intervertebral disc degeneration using MRI images has been developed.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/