Wim Van Criekinge,Gerrit Meijer,Josef Straub,Beatriz Pinto Morais De Carvalho
申请号：
US12303153
公开号：
US20120196827A1
申请日:
2007.06.12
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Using a combination of analytic methods epigenetic silencing of markers in cancer have been determined. The cancers are generally those of the gastrointestinal tract including but not limited to esophageal, head and neck, gastric, pancreas, liver, and colon. The genes can be used for the early detection of cancer or can be used to identify adenomas that will likely progress to carcinomas. Therapeutic regimens based on the epigenetic silenced genes can be chosen and/or monitored. Kits for evaluating epigenetic silencing of these genes can be used for detection and monitoring.
