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9-AMINOMETHYL MINOCYCLINE COMPOUNDS AND USES THEREOF
专利权人:
Paratek Pharmaceuticals; Inc.
发明人:
S. Ken Tanaka,Evangelos L. Tzanis,Lynne Garrity-Ryan,Amy L. Manley
申请号:
US15667683
公开号:
US20180055859A1
申请日:
2017.08.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods and compositions for using a tetracycline compound to treat bacterial infections are described. In one embodiment, for example, the invention provides a method of treating a subject for an infection, comprising administering to said subject an effective amount of 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt thereof, such that said subject is treated, wherein the 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline is administered orally at a dose of about 450 mg per day for two consecutive days, then at a dose of about 300 mg per day for 5 or more days.
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