Thiazole derivatives featuring an imidazolidine or triazole derivative as inhibitors of stearoyl-CoA desaturase

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专利权人:

NOVARTIS AG

发明人:

CHOWDHURY, SULTAN,DALES, NATALIE,FONAREV, JULIA,FU, JIANMIN,HOU, DUANJIE,JIA, QI,KODUMURU, VISHNUMURTHY,POKROVSKAIA, NATALIA,SUN, SHAOYI,ZHANG, ZAIHUI

申请号：

NZ58735009

公开号：

NZ587350A

申请日:

2009.02.18

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Heterocyclic thiazole derivatives of formula (I) that modulate the activity of stearoyl-CoA desaturase (SCD) enzymes are disclosed, wherein the variables are as defined in the specification. These compounds are suitable for treating diseases related to elevated lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome, dermatological disorders and the like.

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