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Pluripotent embryonic-like stem cells, compositions, methods and uses thereof
专利权人:
エイビーティー ホールディング カンパニー
发明人:
ヘンリー イー ヤング,ポール エイ ルーカス
申请号:
JP2015225380
公开号:
JP6539188B2
申请日:
2015.11.18
申请国别(地区):
JP
年份:
2019
代理人:
摘要:
The present invention relates to pluripotent stem cells, particularly to pluripotent embryonic-like stem cells. The invention further relates to methods of purifying pluripotent embryonic-like stem cells and to compositions, cultures and clones thereof. The present invention also relates to a method of transplanting the pluripotent stem cells of the present invention in a mammalian host, such as human, comprising introducing the stem cells, into the host. The invention further relates to methods of in vivo administration of a protein or gene of interest comprising transfecting a pluripotent stem cell with a construct comprising DNA which encodes a protein of interest and then introducing the stem cell into the host where the protein or gene of interest is expressed. The present invention also relates to methods of producing mesodermal, endodermal or ectodermal lineage-committed cells by culturing or transplantation of the pluripotent stem cells of the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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