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N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal products
专利权人:
BAYER PHARMA AKTIENGESELLSCHAFT
发明人:
BADER BENJAMIN,NGUYEN DUY,FAUS GIMENEZ HORTENSIA,KÖHR SILKE,FRITSCH MARTIN,KÜNZER HERMANN
申请号:
NZ70310013
公开号:
NZ703100A
申请日:
2013.06.24
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
The present invention relates to compounds of general formula (I), in which: R1 stands for H, cyano, fluorine, chlorine or bromine; A stands for phenyl or 5-membered heteroaryl, wherein this phenyl or this 5-membered heteroaryl is optionally substituted with one, two or three substituents selected independently of one another from: halogen, cyano, alkyl-, haloalkyl-, cycloalkyl-, heterocyclyl-, hydroxy, alkoxy-, fluoroalkoxy-, cycloalkyloxy-, amino-, alkylamino-, dialkylamino-, cycloalkylamino-, alkylcycloalkylamino-, dicycloalkylamino-, alkylcarbonylamino-, cycloalkylcarbonylamino-, alkylsulphanyl-, cycloalkylsulphanyl-, alkylsulphonyl-, cycloalkylsulphonyl-, aminosulphonyl-, alkylaminosulphonyl-, cycloalkylaminosulphonyl-; alkoxycarbonyl-; n = 0, 1 or 2; or one of their salts, of their solvates or of the solvates of their salts.
来源网站:
中国工程科技知识中心
来源网址:
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