Luis BRITO,Michelle C. ARCHER,Andrew GEALL,Derek O'HAGAN,Manmohan SINGH
申请号:
US16401452
公开号:
US20190254968A1
申请日:
2019.05.02
申请国别(地区):
US
年份:
2019
代理人:
摘要:
This invention generally relates to cationic oil-in-water emulsions that can be used to deliver nucleic acid molecules, such as an RNA molecule. The emulsion particles comprise an oil core and a cationic lipid. The emulsion particles have an average diameter of about 80 nm to about 180 nm, and the emulsion have an N/P ratio of at least 1.1:1.