University of Pittsburgh - Of the Commonwealth System of Higher Education
发明人:
Farzad Esni,Jing Hu
申请号:
US16485773
公开号:
US20200046700A1
申请日:
2018.02.12
申请国别(地区):
US
年份:
2020
代理人:
摘要:
It is disclosed herein that a FAK inhibitor induces conversion of acinar cells into beta cells. Methods are provided for increasing beta cell proliferation by administering an effective amount of a FAK inhibitor to a subject in need thereof. Methods are also provided for treating a subject with diabetes or at risk of developing diabetes, comprising administering to the subject a therapeutically effective amount of a FAK inhibitor.