Jae Min Jeong,Myung Chul Lee,June Key Chung,Dong Soo Lee
申请号:
US13146280
公开号:
US08911706B2
申请日:
2010.01.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is about bifunctional chelating agents (BCA) conjugated mannosyl human serum albumin (MSA) and its radioisotope labeled compounds for imaging immune system such as macrophages, Kupffer cells, reticuloendothelial system (RES), and lymphatic system. The present invention comprises BCA-MSA conjugates, their radiolabeled compounds, and kits for radiolabeing. The present invention improved radiolabeling procedure, showed higher lymphatic system uptake, and enabled image by positron emission tomography (PET).