The invention provides container systems, kits and methods for peritoneal dialysis(PD) solutions. Such a system, for example, includes a first compartment thatcontains a PD osmotic agent and a second compartment that contains a PD bufferagent. The compartments maintain their respective contents separately fromone another for purposes of transport, storage and/or sterilization. However,the compartments are fluidly couplable, so that their respective contents canbe combined with one another, e.g., following sterilization of the agents andprior to their introduction into the patients abdomen. The inventionprovides, in other aspects, such systems, kits and methods that provide protectivestructure which inhibits breaking of a seal prior between the second compartmentand an outlet of the system, prior to breaking of a seal between the first and secondcompartments.
