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Antimicrobial and immunostimulator system that includes an oxidoreductase enzyme
专利权人:
INSTITUTE OF TECHNOLOGY SLIGO
发明人:
BARRETT, JOHN REGINALD,BRENNAN, JAMES JOSEPH,PATTON, THOMAS PATRICK
申请号:
ES07827107
公开号:
ES2384654T3
申请日:
2007.10.05
申请国别(地区):
ES
年份:
2012
代理人:
摘要:
Stable immunostimulant and antimicrobial storage system that includes glucose oxidase, D-glucose, added sugars selected from one or more of sucrose, fructose and / or maltose and hydrogen peroxide in an aqueous solution, in which glucose or xidase It is present in an activity of at least U for 100g of the system; D-glucose is present from 20 to 85% by weight, based on the total system weight; additional sugars chosen from one or more among the sucrose, fructose and / or maltose are present from 5 to 70% by weight, with respect to the weight of the total system, water is present from 10 to 20% by weight, with respect to the weight of the total system; the system has a pH of approximately 4 to 8; and in which the system facilitates a release of hydrogen in dosetapas in which (a) the hydrogen peroxide produced endogenously and stable in its storage is bioavailable in the system with an index of at least 10 mg per liter for a immediate release; and (b) the prolonged release of additional hydrogen peroxide for at least a period of twenty-four hours, occurs at the time of rehydration of the system.Sistema inmunoestimulante y antimicrobiano estable en su almacenamiento que incluye glucosa oxidasa, D-glucosa,azúcares añadidos elegidos entre uno o varios entre la sacarosa, la fructosa y/o la maltosa y peróxido de hidrógeno enuna solución acuosa, en el que la glucosa o xidasa se encuentra presente en una actividad de, al menos, U para 100gdel sistema;la D-glucosa se encuentra presente de un 20 a un 85% en peso, respecto al peso del sistema total;los azúcares adicionales elegidos entre uno o varios entre la sacarosa, la fructosa y/o la maltosa se encuentranpresentes de un 5 a un 70% en peso, respecto al peso del sistema total;el agua se encuentra presente de un 10 a un 20% en peso, respecto al peso del sistema total;el sistema tiene un pH aproximadamente de 4 a 8; y en el que el sistema facilita una liberación de hidrógeno en dosetapas en la que(a) el peróxido de hidrógeno pro
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