VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS; WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG
发明人:
CARETTE, JAN, EDUARD,VAN BEUSECHEM, VICTOR, WILLEM
申请号：
DK05732404
公开号：
DK1749097T3
申请日:
2005.04.15
申请国别(地区):
DK
年份:
2012
代理人:
摘要：
Described is a replication competent virus, being capable to replicate and having lytic capacity in target cells, the virus comprising in the genome thereof, at least one DNA sequence coding for a silencing factor functional in reducing expression of a target gene in the said target cells, operably linked to one or more expression control sequences, functional in the said target cells, and the use thereof in the preparation of a medicament and to the use thereof in a method for lysing target cells expressing a virus inhibitory factor.
