Problem of the present invention is that exploitation prefilled syringe without losing " caoutchouc elasticity " guarantee " sealing characteristics ", can also reach height " water vapour impermeability. using " silicon rubber, this " can be realized adequately " slidability " in this way" this prefilled syringe (one), it is characterised in that be by formed below: injector cartridge (1) has internal filled with drug solution (30) Washer (10), these are press-fitted into injector cartridge (1) This washer (10) is connected to plunger rod (5). Drug solution is shown resistance (30) and syringe cylinder (1) and is filled by the washer (10) by thermosetting resin drug solution. Main part (26) of the groove (18) along entire periphery sliding contact surface (11), syringe cylinder (1) of these sliding parts along inner peripheral surface (2). Sliding contact ring (19), these are cooperated to groove (18), these sliding parts are along inner peripheral surface (2) injector cartridge, by being added, to silicon rubber base-material, silicone oil, spherical super high molecular weight fine powder.