Sen, Chandan,Rink, Cameron,Roy, Sashwati,Christoforidis, Greg
申请号：
AU2013271440
公开号：
AU2013271440A1
申请日:
2013.06.07
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The present invention provides methods of promoting arteriogenesis in a subject. Embodiments include methods comprising: administering an effective dose of tocotrienol to the subject causing an increase in Tissue Inhibitor of Metalloproteinase Metallopeptidase Inhibitor 1 (TIMP1) in vessels of cerebrovascular collateral circulation in the subject attenuating the activity of Matrix Metalloproteinase-2 (MMP2) thereby promoting arteriogenesis.
