ADMINISTRATION MÉTRONOMIQUE AVEC AMPLIFICATION DE LA CONVECTION D'UNE CHIMIOTHÉRAPIE INTRATHÉCALE À L'AIDE D'UNE POMPE DE RESPIRATEUR MAGNÉTIQUE (MBP) POUR LE TRAITEMENT DE LA CARCINOMATOSE LEPTOMÉNINGÉE
A magnetically controlled pump is implanted into the cerebrospinal fluid of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled lumen, intratumoral catheter which will be implanted. Spinal fluid drawn from the patient is analyzed. Medication is delivered on a continuous metronomic basis into the CSF via an internalized pump. CSF is removed and analyzed for VEGF and other cytokines via spectrophotometer analysis or a lab on a chip. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.
