NEW TYPE OF CYTIDINE DERIVATIVE AND APPLICATION THEREOF

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专利权人:

Changzhou Fangyuan Pharmaceutical Co.; Ltd.

发明人:

YANG, Daria,WANG, Haidong,LIU, Xin,WANG, Huijuan,LIEW, Siong Tern

申请号：

EP15860978

公开号：

EP3210992A4

申请日:

2015.06.09

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present disclosure provides a new cytidine derivative having the general formula (I), and applications thereof: R1 As demonstrated by experiments on the growth inhibition effect of the new cytidine derivative of the present invention on HCT-116 colon cancer xenografts in tumor-bearing nude mice , the compound of the present invention has high anti-tumor activity, data of impacts on weight of nude mice bearing human colon cancer HCT-116 and data of mortality rate showed that the toxicity of the compound is comparatively low.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/