Polymer nanoparticle of Finasteride and minoxidil, Preparation Process, Aqueous suspension containing the same, Pharmaceutical Composition and its use.
The present invention relates to a pharmaceutical composition for topical application for the treatment of alopecia, said composition comprising polymeric nanoparticles, preferably nanocapsules containing two active ingredients, finasteride and minoxidil, additives and a pharmaceutically acceptable carrier. The invention further includes a process for the preparation of polymeric nanoparticles, preferably nanocapsules of finasteride and minoxidil, a composition suitable for topical application for the treatment of alopecia, as well as the use of said nanocapsules for the preparation of a pharmaceutical composition.<；p>；Nanopartí；cula polimé；rica en la forma de nanocapsoide que comprende los principios activos finasterida y minoxidil, formada a partir de: (i) la Fase orgá；nica comprende: (a) un polí；mero hidrofó；bico, (b) un aceite fijo, (c) por lo menos un tensoactivo lipofí；lico de bajo EHL, (d) un solvente orgá；nico, (e) un co-solvente y (f ) finasterida, y (ii) la Fase acuosa comprende: (g) por lo menos un tensoactivo hidrofí；lico, (h) minoxidil, y (i) agua.<；/p>；
