This document describes techniques for gripping a guidewire (12). In one example, a device (30) includes an elongated handle (14) defining a handle lumen extending from a distal handle end to a proximal handle end, a handle insert (32,34,36) having a length and being configured to be inserted into the handle lumen, wherein a handle insert material is more compliant than a handle material, and wherein the handle insert defines a guidewire lumen configured to receive a guidewire, and a cap (16) configured to compress the handle insert to grip the guidewire along a substantial portion of the length of the handle insert.
