An endoscope clamping assembly includes an adjustable joint supporter and a clamper; the clamper includes a base, an upper pressure plate, a lower pressure plate, and a clamped by the upper pressure plate and the lower pressure plate Tight ball, a shaft, and a knob. When the knob is not locked, the tightening ball can rotate between the upper pressure plate and the lower pressure plate to adjust the angle, direction and insertion depth of the endoscope; and when the knob is locked, the upper pressure plate And/or the lower pressure plate is subjected to an axial pressure, so as to cause the upper pressure plate and the lower pressure plate to produce a radial squeezing effect on the tightening ball together, and cause the deformation and contraction of the tightening ball to clamp the inner glass.一種內視鏡夾持總成,其包括一可調式接合支撐器和一夾持器;該夾持器包括一基座,一上壓板,一下壓板,一被該上壓板和該下壓板包夾的束緊球,一支軸,以及一旋鈕。當該旋鈕未鎖緊時,該束緊球能在該上壓板和該下壓板之間旋轉以調整該內視鏡的角度、方向和插入深度;另當該旋鈕鎖緊時,使該上壓板及/或該下壓板受到一軸向壓力,以促使該上壓板和該下壓板一起對該束緊球產生徑向擠壓作用,並造成該束緊球的變形和內縮以夾持該內視鏡。