Jiangsu Hengrui Medicine Co., Ltd.,;Shanghai Hengrui Pharmaceutical Co., Ltd.,
发明人:
LU Biao,SHEN Xiaodong,HE Mingxun,LIU Dong,ZHANG Minsheng
申请号:
SI201630514
公开号:
SI3378859T1
申请日:
2016.11.02
申请国别(地区):
SI
年份:
2020
代理人:
摘要:
The present invention relates to a benzofuran derivative, a preparation method thereof and a use thereof in medicine. In particular, the present invention relates to the benzofuran derivative as shown by general formula (I), the preparation method thereof, a pharmaceutical composition containing the derivative, and uses thereof as an EZH2 inhibitor and in the prevention and/or treatment of diseases such as tumours and cancers, etc., and in particular uses thereof in the prevention and/or treatment of non-Hodgkin's lymphoma, diffuse large B-cell lymphoma, follicular lymphoma and synovial sarcoma, wherein the definitions of the substituents in the general formula (I) are the same as those defined in the description.