STEVANOVIC, STEFAN,GOUTTEFANGES, CECILE,RAMMENSEE, HANS-GOERG,WEINSCHENK, TONI,LEWANDROWSKI, PETER
申请号:
CA2724198
公开号:
CA2724198C
申请日:
2009.05.14
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to peptides, nucleic acids, and cells for use inimmunotherapeutic methods. In partic-ular,the present invention relates to the immunotherapy of cancer. The presentinvention furthermore relates to survivin-derivedtumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or incombination with other tumor-associated peptides that serveas active pharmaceutical ingredients of vaccine compositions that stimulateanti-tumor immune responses. The present inventionspecifically relates to three novel peptide sequences and variants thereofderived from HLA class I and class II molecules of hu-mantumor cells that can be used in vaccine compositions for eliciting anti-tumorimmune responses.