A serpentine surgical instrument, comprising: a handheld end (1), a swappable instrument (2), and a quick-swap structure (3), where the handheld end (1) comprises a grip structure (11), a wrist structure (14), and a control structure (12)； the control structure (12) is connected to the grip structure (11) via the wrist structure (14), the wrist structure (14) has at least one degree of freedom to swing； the swappable instrument (2) comprises a serpentine structure (21), a tool support base (22) and an end effector (23)； the quick-swap structure (3) comprises a first Hooke hinge (321) provided on the grip structure (11) and a connector (322) provided on the swappable instrument (2), the first Hooke hinge (321) and the connector (322) are detachably connected to implement the transmission or cutoff of power； and, a transmission apparatus (6), comprising a first part and a second part, respectively arranged on the swappable instrument (2) and the handheld end (1), the first part being connected to the connector (322) and to the serpentine structure (21), and the second part being connected to the wrist structure (14) and to the first Hooke hinge (321). A detachable connection is implemented between the handheld end (1) and the swappable instrument (2) via the quick-swap structure (3), quick swapping is implemented, the quick-swap structure (3) implements the transmission and cutoff of power via the Hooke hinge structure, and the design is simple.L'invention concerne un instrument chirurgical en serpentin, comprenant : une extrémité tenue à la main (1), un instrument interchangeable (2) et une structure à permutation rapide (3), l'extrémité tenue à la main (1) comprenant une structure de préhension (11), une structure de poignet (14) et une structure de commande (12) ； la structure de commande (12) est reliée à la structure de préhension (11) par l'intermédiaire de la structure de poignet (14), la structure de poignet (14) a au moins un degré de liberté pour osciller ；
