A system for generating at least one standard ECG lead, comprising: a plurality of electrodes (101-103； 301-305 403) for application to a subject at separate points therefrom, wherein said plurality of electrodes is grouped in a first (101, 403； 301, 403) and a second (101-103； 301-305) group； connections (111, 400, 401) that allow a physical and electrical connection and disconnection of electrodes of said first group of electrodes with each other and from each other； a remote receiving station (200) having generator means for generating at least one standard ECG lead from signals detected by said first group of said plurality of electrodes； a plurality of wireless ECG detection units (100； 300) each comprising: a radio module (124) for communication with said remote receiving station (200)； and at least three proximally located nonlinear electrodes belonging to said second group of said plurality of electrodes, wherein said three proximally located nonlinear electrodes are arranged to detect two local bipolar signals substantially simultaneously with the signals detected by the first group of said plurality of electrodes, wherein said system further comprises: means for generating for each plurality of wireless ECG detection units at least two non-standard ECG signals from bipolar signals, wherein said radio module of each of said wireless ECG detection units is arranged to wirelessly transfer said two bipolar signals and said at least two standard ECG signals to said remote receiving station； processor means (202) at said remote receiving station (200) for transforming computation that synthesizes the standard ECG leads generated by generator means from said at least two standard ECG signals； wherein said processor means (202) is further arranged to synthesize said at least one standard ECG lead from said non-standard ECG signals solely using said transformation upon disconnection of the electrodes of said first group of electrodes from each other； whereby said s
