INGÉNIERIE GÉNOMIQUE AVEC SYSTÈMES CRISPR DE TYPE I DANS DES CELLULES EUCARYOTES

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专利权人:

Duke University;North Carolina State University

发明人:

GERSBACH, Charles, A.,PICKAR, Adrian,BEISEL, Chase

申请号：

EP16856228

公开号：

EP3362571A4

申请日:

2016.10.13

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Disclosed herein are Type I Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) system related compositions and methods of using said Type I CRISPR/Cas system related compositions for altering gene expression and genome engineering. The invention relates to compositions comprising Type I CRISPR-Cas polypeptides and CRISPR array nucleic acids designed for genome modification in eukaryotic cells and for targeted killing of eukaryotic cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/