Cytune Pharma;INSERM (Institut National De La Sante Et De La Recherche Medicale)
发明人:
Sebastien Daniel Morisseau,Geraldine Teppaz,Yannick Laurent Joseph Jacques,Bruno Gilbert Marc Robert,Guy Luc Michel De Martynoff,David Bechard
申请号：
US15214032
公开号：
US10626155B2
申请日:
2016.07.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and (ii) a polypeptide comprising the amino acid sequence of the sushi domain of the interleukin 15R alpha (IL-15Rα) or derivatives thereof； and uses thereof.
